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AzithromycinSuspension
(5%=500mg/10ml)
1.Formulations
I.Azithromycindihydrate.............................5.0g Sodiumcitrate..........................................5.0g Citricacid................................................2.0g Sucrose.................................................60.0g KollidonCL-M[1].....................................9.0g
II.CremophorRH40[1]...............................0.5g Chocolateflavour....................................0.2g Water.....................................................10.0g III.Water................................................ad100ml
2.Manufacturing AddthemixtureIto thesolutionIIandfillwithwaterto ato talvolumeof
100mlshakingverywell.
3.Propertiesofthesuspensions
Light-brownsuspensionshowingnosedimentationduring24hoursand
goodredispersibility.ThebittertasteofAzithromycinisalmostcompletely
masked.
关键字:azithromycin suension
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