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Sucralfate SodiumA1ginateTablets
(500mg 20mg)
1.Formulation
I.Sucralfate...............................................500g Sodiuma1ginate........................................20g Cornstarch[3]..........................................70g
II.Kollidon30[1]...........................................20g Ethanol95%...........................................80ml
III.KollidonCL[1]..........................................30g Magnesiumstearate[2]...............................3g 2.Manufacturing(Wetgranulation)
GranulatemixtureIwithsolutionII,pass throughasieve,mixthedry
granuleswithIIIandpresswithlowcompressionforce.
3.Tabletproperties
Weight.................................................660mg Diameter...............................................12mm
Form...................................................biplanar
Hardness..................................................90N
Disintegration.....................................3–4min
Friability...................................................0.3%
关键字:sucralfate sodium alginate
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