PolidocanolWoundSpray (0.5%) 1.Formulation I.Polidocanol.................................................1g KollidonVA64[1]......................................10g Ethocel20(Dow)....................................10g LutrolE400[1]...........................................4g
II.Ethylacetate...........................................135g Isopropanol...............................................40g 2.Manufacturingofthesolution DissolvethecomponentsIinthesolventmixture
II. 3.Manufacturingofthespray Fillthesolutioninto spraycanswiththenecessaryquantityofpropellant (e.g.propane/butane)orinamechanicalpumpbottle.
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