AlprazolamTablets
（0.5mg）
1.Formulation
Alprazolam...............................................0.5g Ludipress[1]...........................................148g Magnesiumstearate[2]...............................1g 2.Manufacturing（Directcompression）
Mixallcomponents,sievethrougha0.8mmscreenandpresswithlow
compressionforce.
3.Tabletproperties
Weight.................................................158mg Diameter.................................................8mm
Form...................................................biplanar
Hardness................................................106N
Disintegration..........................................3min
Friability.................................................<0.1%
4.Remark
Ifthecontentuniformitydoesnotmeettherequirementsitwouldbe
recommendedto prepareapremixoftheactiveingredientwithasmall
parto ftheLudipressorwithlacto semonohydratebeforemixingwiththe
othercomponentsoftheformulation.
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