Beta Carotene Effervescent Tablets
（7 mg）
1. Formulation
Lucarotin dry powder 10 % CWD （BASF） ..70 g
Ludipress [1]............................................113 g
Citric acid, anhydrous ..............................200 g
Sodium bicarbonate.................................120 g
Sodium carbonate .....................................12 g
Sodium cyclamate .....................................20 g
Aspartame ................................................15 g
Orange flavour ..........................................20 g
Polyethylene glycol 6000, powder [6]..........30 g
2. Manufacturing （Direct compression）
Pass all components through o 0.8 mm sieve, mix and press with
medium or high compression force at maximum 30 % of relative atmospheric
humidity.
3. Tablet properties
Compression force
18 kN 26 kN
Weight ......................................................602 mg 605 mg
Diameter ....................................................12 mm 12 mm
Form ........................................................biplanar biplanar
Colour.........................................................brown brown
Hardness ......................................................81 N 108 N
Disintegration （water） ..................................45 sec 50 sec
Friability .......................................................0.4% 0.2%
关键字：beta carotene effervescent
