SugarCoating,manual
1.Formulations
No.1No.2
WhiteColoured
Kollidon30[1].............................................16.8g16.8g Carmelosesodium.......................................14.6g14.6g Aerosil200[4].............................................10.7g10.7g Talc............................................................81.0g81.0g PolysorbateorCremophorRH40[1]..............5.3g5.3g SicovitTitaniumdioxide[1].............................70g115.0g SicovitIronoxide[1]............................................–17.3g Sucrose....................................................3,135g3,135g Water........................................................1,650g1,650g 2.Manufacturingofthecoatingsuspensions
DissolveKollidon,PolysorbateorCremophorandsucroseinthewater
andsuspendtheothercomponentsinthissolution.Mixinacolloidmill.
3.Applicationofthecoatingsuspension
StartwithformulationNo.1bymeansofthemanualsugarcoating procedureduringsomehours.Afterchangingto formulationNo.2continue
withthesameprocedureuntilhomogeneouscolouredsugarcoated
tabletsareobtained.
4.Remark
Thepolishingcanbedonebymeansofasolutionofbeeswaxorpolyethylene
glycol6000.
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