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Povidone-IodineGel-Cream (10%) 1.Formulation I.PVP-Iodine30/06(BASF)........................10.0g II.Citricacidsolution,0.1molar..................35.9g NA2HPO412H2Osolution,0.2molar......18.1g LutrolE400[1].........................................5.0g III.Liquidparaffin.........................................10.0g IV.LutrolF127............................................15.0g V.LutrolF127..............................................7.0g 2.Manufacturing DissolveIinsolutionII,mixwithIIIanddissolveIVatabout20C.Cool to 5–8CanddissolveV.Maintaincooluntilallairbubblesdisappeared. 3.Properties Brownturibgel. 4.Chemicalstability(20–25C) 0Months3Months6Months pH3.43.13.1 Availableiodine1.0%0.99%0.95% Lossofiodine–1%5% Viscosity(Brookfield)113000mPas124000mPas122000mPas
关键字:povidone iodine gel
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