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MultivitaminOralGel 1.Formulation I.VitaminApalmitate...............................110mg 1.7Mio.i.u./g(BASF) VitaminEacetate(BASF)....................1,060mg Butylhydroxyto luene..............................500mg CremophorRH40[1]................................20g II.Water......................................................725g III.Thiaminehydrochloride(BASF)..............355mg Riboflavin(BASF)....................................35mg Pyridoxinhydrochloride(BASF)..............177mg Cyanocobalamingelatincoated1%.........35mg (BASF) Nicotinamide........................................353mg Folicacid...............................................35mg Dexpanthenol(BASF)............................353mg EDTAsodium........................................300mg Ferroussulfate(7H2O)........................438mg Manganesechloride(4H2O)................638mg Potassiumiodide..................................115mg IV.Kollidon90F[1]........................................50g LutrolF127[1]........................................100g VLutrolF127[1]........................................100g to talamount:...............................about1000g 2.Manufacturing HeatmixtureIto about60Cto obtainaclearsolution,addslowlythe waterIIto thewellstirredsolutionI,dissolveIIIandIVinthismixed solutionatroomtemperature,coolto about6C,addVandstirruntilall LutrolF127isdissolved.Maintainthecooltemperatureuntiltheair bubblesescaped.3. Properties of the gelColour ........................................yellow-orangeClarity .............................................opalescentpH-value.....................................................4.3Consistency......................................semi-solid
关键字:multivitamin oral gel
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