MultivitaminChewableTabletsforChildren
1.Formulation
VitaminAacetatedrypowder....................7.0g 500000i.u./g(BASF)
Thiaminemononitrate(BASF)....................1.2g Riboflavin(BASF)......................................1.2g Nicotinamide..........................................20.0g Pyridoxinehydrochloride(BASF)................1.8g Cyanocobalamin0.1%drypowder............6.5g (BASF)
Ascorbicacid,powder(BASF).................60.0g VitaminD3acetatedrypowder
100000i.u./g(BASF)...............................5.0g VitaminEacetate..................................31.0g drypowderSD50(BASF)
Sorbito l,crystalline[10].........................200.0g Sucrose,crystalline...............................200.0g KollidonVA64[1]...................................20.0g Aerosil200[4]..........................................1.0g Orangeflavour,drypowder.....................30.0g Raspberryflavour,drypowder...................6.0g pass ionfruitflavour,drypowder................3.0g Cyclamatesodium....................................2.0g 2.Manufacturing(Directcompression)
Mixallingredients,pass througha0.8mmsieveandpresswithmedium
to highcompressionforce(20kN).
3. Tablet properties
Weight .................................................575 mg
Diameter ...............................................12 mm
Form ...................................................biplanar
Hardness ................................................100 N
Disintegration ..........................................7 min
Friability...................................................0.2%
关键字:multivitamin chewable tablets