MeprobamateTablets
(400mg),DC
1.Formulation
Meprobamate..........................................400g AvicelpH101[5].......................................80g Cornstarch[3]..........................................30g KollidonVA64[1]......................................20g KollidonCL[1]..........................................20g Talc[10]......................................................7g Magnesiumstearate[2]...............................3g 2.Manufacturing(Directcompression)
Mixallcomponents,pass througha0.8mmsieveandpresswithhigh
compressionforce(20KN).
3.Tabletproperties
Weight.................................................560mg Diameter...............................................12mm
Form...................................................biplanar
Hardness..................................................90N
Disintegration......................................<10min
Friability..................................................0.6%
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