ChloroquineTablets （250mg） 1.Formulation I.Chloroquinediphosphate.........................250g Dicalciumphosphate,DI-TAB[9]..............100g
II.Kollidon30[1]...........................................10g Isopropanol...............................................83g III.KollidonCL[1]...........................................10g Aerosil200[4].............................................2g Talc[10]......................................................3g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,dry,pass througha0.8mmsieve, addthemixtureIIIandpresswithlowcompressionforce. 3.Tabletproperties Weight.................................................361mg Diameter.................................................8mm Form...................................................biplanar Hardness................................................202N Disintegration..........................................8min Friability................................................<0.1%
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