CharcoalTabletsI （250mg） 1.Formulation I.Activatedcharcoal..................................250g KollidonVA64............................................50g Sorbit,crystalline[10]...............................110g
II.Acaciagum...............................................50g Water.....................................................275g III.LutrolE4000F[1].........................................2g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,pass througha0.8mmsieve,dry untiltherelativepowderhumidityof40–50%isreached,pass again througha0.8mmsieve,mixwithIIIandpresswithhighcompression force. 3.Tabletproperties Weight.................................................447mg Diameter...............................................12mm Form...................................................biplanar Hardness.................................................27N Disintegration..........................................7min Friability...................................................0.5%
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