FamotidineTablets
(40mg)
1.Formulations
No.1No.2
Famotidine.....................................................40g40g Ludipress[1]................................................105g104g Magnesiumstearate[2]....................................3g–
Stearicacid[7]....................................................–2g Aerosil200[4]..................................................4g4g 2.Manufacturing(Directcompression)
Mixallcomponents,pass througha0.8mmsieveandpresswithlow
compressionforce.
3.Tabletproperties
No.1No.2
Weight......................................................149mg148mg Diameter......................................................8mm8mm
Form........................................................biplanarbiplanar
Hardness......................................................74N49N
Disintegration(gastricjuice)...........................3min1min
Friability......................................................<0.1%0.3%
Dissolution(10min)........................................63%nottested
(30min).......................................95%nottested
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