Eto phylline TheophyllineTablets
(100mg 22mg),DC
1.Formulation
Eto phylline,powder.................................101g Theophylline,anhydrous0,2/0,7(BASF).....23g Ludipress[1].............................................53g Magnesiumstearate[2]...............................1g Aerosil200[4].............................................2g 2.Manufacturing(Directcompression)
Mixallcomponents,pass througha0.8mmsieveandpressto tablets
withlowcompressionforce.
3.Tabletproperties
Weight.................................................175mg Diameter.................................................8mm
Form...................................................biplanar
Hardness................................................102N
Disintegration......................................7–8min
Friability...................................................0.2%
4.Remark
to enhancetheflowabilityofthetablettingmixturetheamounto fAerosil
200couldbeincreased.
关键字:etophylline theophylline tablets