SulfathiazoleTablets
（250mg）
1.Formulations
No.1No.2
I.Sulfathiazole................................................250g250g Lacto semonohydrate[8]..............................237g–
Dicalciumphosphate[9]......................................–237g Kollidon30[1]................................................12g12g
II.Water.............................................................q.s.q.s.
III.KollidonCL[1]...............................................12g12g Magnesiumstearate[2]...............................2–3g2–3g 2.Manufacturing（Wetgranulation）
GranulatemixtureIwithsolventII,pass througha0.8mmsieve,dry,
addIIIandpresswithlowcompressionforce.
3.Tabletproperties
Weight......................................................504mg512mg Diameter....................................................12mml2mm
Form........................................................biplanarbiplanar
Hardness.....................................................115N154N
Disintegration...............................................1min<1min
Friability.......................................................0.2%0.2%
Dissolution,10min........................................80%69%
20min........................................96%90%
关键字：sulfathiazole tablets
