PropranololTablets
（10mg,50mgand100mg）
1.Formulation
No.1:No.2:No.3:
10mg50mg100mg Propranololhydrochloride............10g50g100g Ludipress[1].............................490g450g400g Magnesiumstearate[2]..............2.5g2.5g2.5g 2.Manufacturing（Directcompression）
Mixallcomponents,pass througha0.8mmsieveandpresswithlow
compressionforce.
3.Tabletproperties
No.1No.2No.3
Weight...................................514mg496mg505mg Diameter.................................12mml2mml2mm
Form.....................................biplanarbiplanarbiplanar
Hardness..................................112N86N101N
Disintegration............................2min2min3min
Friability....................................0.1%0.2%0.1%
4.Remarks
–InthecaseofformulationNo.1orNo.2theamounto fLudipressand
thetabletweightcouldbereduced.
–Theseformulationscanbeusedfortabletcores,to o.
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