Magaldrate Chewable Tablets

MagaldrateChewableTablets （500mg） 1.Formulation I.MagaldrateUSP......................................500g Lacto semonohydrate[8].........................400g Orangeflavour（FDO）.................................50g II.Kollidon90F[1]........................................20g Bananaflavour（FDO）...................................6g Cocosflavour（FDO）....................................6g Saccharinsodium........................................1g Water......................................................180g III.Aerosil200[4].............................................5g Magnesiumstearate[2]...............................3g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,pass througha0.8mmsieve,dry, mixwithIIIandpresswithlowcompressionforce. 3.Tabletproperties Weight................................................1000mg Diameter...............................................16mm Form...................................................biplanar Hardness..................................................72N Disintegration（water）.............................60min Friability................................................<0.1% Taste.......................................................good