Dimenhydrinate Tablets
（50 mg）, DC
1. Formulation
Dimenhydrinate .........................................50 g
Aerosil 200 [4] ..........................................4.0 g
Ludipress [1] ...........................................140 g
Kollidon CL [1] .........................................2.0 g
Magnesium stearate [2].............................1.5 g
2. Manufacturing （Direct compression）
Mix dimenhydrinate with Aerosil 200, add the other components, sieve
and press with low compression force.
3. Tablet properties
Weight .................................................202 mg
Diameter .................................................8 mm
Form ...................................................biplanar
Hardness..................................................76 N
Disintegration .........................................3 min
Friability .................................................<0.1%
Dissolution in water （USP, 15 min ...............91%
30 min ...............93%
45 min ...............94%
关键字：dimenhydrinate tablets
