VitaminB2(Riboflavin)Tablets
(10mg)
1.Formulation
I.Riboflavin(BASF).........................................10.0g Lacto semonohydrate[8].............................75.0g Cornstarch[3]............................................20.0g AvicelpH101[5].........................................15.0g
II.Kollidon30[1]..................................................5g Water............................................................25g III.Aerosil200[4]...............................................0.8g Talc[10]........................................................2.5g Hydrogenatedcasto roil(Henkel)....................1.7g 2.Manufacturing(Wetgranulation)
GranulatemixtureIwithsolutionII,dry,pass througha0.8mmsieve,
mixwithIIandpresswithlowcompressionforce.
3.Tabletproperties
Weight......................................................134mg Diameter......................................................8mm
Form........................................................biplanar
Hardness......................................................82N
Disintegration...........................................1–2min
Friability.....................................................<0.1%
关键字:vitamin tablets