VitaminA VitaminD3 VitaminC
ChewableTabletsforChildren
(2000i.u. 200i.u. 30mg)
1.Formulation
VitaminA D3drypowder......................4.0g 500000 50000i.u./g(BASF)
Ascorbicacid,powder(BASF).................33.0g Sucrose,crystalline...............................300.0g Sorbito l,crystalline[10].........................300.0g Mannito l...............................................300.0g Ludipress[1]........................................300.0g Stearicacid[7].........................................5.0g Saccharinsodium.....................................0.1g Cyclamatesodium..................................30.0g Flavourmixture(Firmenich)......................30.0g Polyethyleneglycol6000,powder[6].......20.0g 2.Manufacturing(Directcompression)
Passallcomponentsthrougha0.8mmsieve,mixandpresswithhigh
compressionforce.
3.Tabletproperties
Weight..............................................1,290mg Diameter...............................................16mm
Form...................................................biplanar
Hardness................................................107N
Disintegration..........................................7min
Friability...................................................0.4%
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