VitaminBComplex VitaminCEffervescent
Tablets
1.Formulation
I.Thiaminemononitrate（BASF）.....................33g Riboflavin（BASF）.........................................4g Pyridoxinehydrochloride（BASF）.................10g Nicotinamide.............................................66g CalciumD-panto thenate（BASF）.................17g Tartaricacid,powder...............................350g Sodiumbicarbonate................................450g Sucrose,crystalline.................................750g Kollidon30[1]...........................................30g
II.Isopropanol................................................q.s.
III.Ascorbicacid,crystalline（BASF）..............500g Riboflavin....................................................3g Cyanocobalamingelatincoated0.1%.........10g Orangeflavour...........................................10g Saccharinsodium........................................2g Cyclamatesodium.......................................5g Polyethyleneglycol6000,powder[6]..........50g 2.Manufacturing（Wetgranulation）
GranulatemixtureIwiththesolventII,dry,pass througha0.8mmsieve,
mixwithIIandpresswithhighcompressionforceatmaximum30%of
relativeatmospherichumidity.
3.Tabletproperties
Weight..............................................2,315mg Diameter...............................................20mm
Form...................................................biplanar
Hardness................................................141N
Disintegration..........................................2min
Friability...................................................0.9%
关键字：vitamin complex
