VitaminC(AscorbicAcid Ascorbate)
ChewableTablets
(500mg)
1.Formulations
No.1No.2
Ascorbicacid,crystalline(BASF)..................500g100g Sodiumascorbate,crystalline(BASF)...................–450g Sorbito l,crystalline[10]..............................1,100g264g Sucrose,crystalline.............................................–200g Sucrose,powder.................................................–200g Dextrose......................................................300g–
Polyethyleneglycol6000,powder[6].............100g60g Magnesiumstearate[2]...................................10g3g Aerosil200[4]................................................10g4g Saccharinsodium...............................................–1g Cyclamatesodium..........................................10g–
Orangeflavour...............................................30g20g 2.Manufacturing(Directcompression)
Passallcomponentsthrougha0.8mmsieve,mixandpresswith
mediumto highcompressionforce.
3.Tabletproperties
No.1No.2
Weight...................................................2,080mg1,295mg Diameter....................................................20mml6mm
Form........................................................biplanarbiplanar
Hardness..................................................>150N126N
Friability.......................................................0.7%0.7%
关键字:vitamin chewable tablets