VitaminBComplex VitaminC
FerrousSulfateTablets
1.Formulation
I.Ferroussulfate(1H20)..............................300g Kollidon30[1]...........................................15g
II.Kollidon30[1].............................................6g 2-Propanol.................................................q.s.
III.Thiaminemononitrate(BASF).....................45g Riboflavin(BASF).......................................10g Pyridoxinehydrochloride(BASF).................82g Nicotinamide.............................................69g Ascorbicacid,powder(BASF)..................470g Ludipress[1]...........................................690g Polyethyleneglycol6000,powder[6]..........50g Aerosil200[4].............................................9g 2.Manufacturing(Wetgranulation)
GranulatethemixtureIwithsolutionII,pass througha0.8mmsieve,mix
withIIIandpresswithhighcompressionforce(25–30kN).
3.Tabletproperties
Weight..............................................1,750mg Diameter...............................................20mm
Form...................................................biplanar
Hardness................................................120N
Disintegration..........................................6min
Friability...................................................0.9%
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