Vitamin B Complex Carnitine Tablet Cores

VitaminBComplex CarnitineTabletCores
1.Formulation
I.Thiaminemononitrate（BASF）..................95.0g Riboflavin（BASF）....................................20.0g Nicotinamide（Degussa）.........................100.0g CalciumD-panto thenate（BASF）..............50.0g Folicacid（Knoll）.......................................2.0g Biotin.......................................................0.2g Cyanocobalamin,gelatincoated1%..........0.5g （BASF）
Carnitinehydrochloride...........................50.0g Inosito l.................................................100.0g Adenosinephosphate...............................2.0g
II.Kollidon30[1]........................................15.7g Isopropanol............................................70.0g III.KollidonCL[1]........................................26.0g Lacto semonohydrate[8].......................122.0g Polyethyleneglycol6000,powder[6].......14.0g 2.Manufacturing（Wetgranulation）
GranulatemixtureIwithsolutionII,dry,pass througha0.8mmsieve,
mixwithIIIandpresswithlowcompressionforce.
3.Tabletproperties
Weight.................................................708mg Diameter...............................................13mm
Form..................................................biconvex
Hardness..................................................88N
Disintegration......................................1–2min
Friability...................................................0.1%