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1.Formulation I.VitaminApalmitate..............................17.0mg 1.7Mioi.u./g(BASF) VitaminD340Mioi.u./g........................0.1mg Butylhydroxyto luene..............................1.0mg CremophorRH40[1]..............................3.00g II.Parabenes..............................................0.10g Water...................................................17.00g III.Thiaminehydrochloride(BASF)................0.05g Riboflavinphosphatesodium..................0.02g Pyridoxinehydrochloride(BASF)..............0.02g Ascorbicacid,crystalline(BASF).............0.25g Water.........................................................5g IV.SugarsyrupUSP...............................ad100ml 2.Manufacturing HeatmixtureIto about65C,stirwellandaddveryslowlythewarm solutionII(65C).MixwithsolutionIIIandaddthesyrup IV. 3.Propertiesofthesyrup Clear,yellowviscousliquid. 4.Physicalstability(20–25Cprotectedfromlight) Nochangeoftheappearanceafter3months.
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