VitaminC（AscorbicAcid Ascorbate）
Lozenges
（250mgand500mg）
1.Formulations
250mg500mg Ascorbicacid,powder（BASF）.........................70g140g Sodiumascorbate........................................208g416g LudipressLCE[1].........................................196g392g Stearicacid[7]...............................................14g28g Orangeflavour.................................................6g12g Saccharinsodium............................................3g6g Aerosil200[4]..................................................3g6g 2.Manufacturing（Directcompression）
Mixallcomponents,pass througha0.8mmsieveandpresswithhigh
compressionforce.
3.Tabletproperties
250mg500mg Weight......................................................505mg1010mg Diameter....................................................12mml6mm
Form........................................................biplanarbiplanar
Hardness......................................................92N116N
Disintegration...............................................5min5min
Friability..........................................................1%0.8%
4.Remark
ThesetabletscouldbecommercializedinEuropeasdietaryfood
becauseallcomponentsareallowedforthisapplication.
关键字：vitamin lozenges
