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Sulfamethoxazole TrimethoprimOral Suspension(400mg 80mg/5ml) 1.Formulations No.1No.2 I.Sulfamethoxazole..........................................8.0g8.0g Trimethoprim.................................................1.6g1.6g KollidonCL-M[1]..........................................3.0g– II.Sucrose......................................................10.0g5.0g LutrolF127orLutrolF68[1]...............................–3.0g Water..........................................................77.0g82.4g III.Vanillin..........................................................0.2gq.s. Chocolateflavour.........................................0.2gq.s. 2.Manufacturing SievethecomponentsI,suspendinsolutionIIandaddtheflavoursIII. 3.Propertiesofthesuspensions No.1No.2 Colour:.........................................................beigebeige Viscosity:.................................................verylowverylow Sedimentationafter2weeks:.............noto bservedveryfew Redispersibilityafter2months:................veryeasyeasy
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