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Tannin-CrospovidoneComplexTablets
(55mg 230mg)
1.Formulation
I.Tannicacid.............................................55.0g Water...................................................230.0g
II.Crospovidone(KollidonCL)[1]..............230.0g III.AvicelpH101[5]....................................33.0g Talc[10]...................................................2.6g Aerosil200[4]..........................................0.3g Calciumarachinate[2]..............................0.3g 2.Manufacturing PreparesolutionI,suspendIIandfiltratetheformedinsolubletannincrospovidone
complex.Washwithwateruntilthewaterisclear,pass the
solidsthrougha0.8mmsieveanddry.AddthecomponentsIIIand
presswithlowcompressionforce.
3.Tabletproperties
Weight.................................................323mg Diameter...............................................12mm
Form...................................................biplanar
Hardness..................................................40N
Disintegration........................................<1min
Friability...................................................0.8%
关键字:tannin croovidone complex
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