VitaminBComplex VitaminCInstant
Granules
（2RDAofVitamins）
1.Formulation
I.Thiaminehydrochloride（BASF）..................1.2g Riboflavinphosphatesodium....................1.9g Nicotinamide（Degussa）..........................15.0g Pyridoxinehydrochloride（BASF）................1.5g Cyanocobalamin,gelatin...........................5.0g coated0.1%（BASF）
Ascorbicacid,powder（BASF）.................50.0g Sucrose...............................................241.0g
II.Kollidon30[1]........................................17.0g Ethanol...................................................60ml
2.Manufacturing MixthecomponentsI,granulatewithsoluito nII,dryandpass througha
0.8mmsieve.
Fill1gofthegranulesinsachets,（or10gin100mlflaksasdrysyrup）.
3.Propertiesofthegranules
Yellowhomogeneousgranulesdispersibleincoldwater.
4.Administration
About1gofthegranules（=1sachet）correspondto twodailyvitaminB
andvitaminCrequirementsofadults.
5. Chemical stability of the granules （20–25 C）
Vitamin After production 4 Months 6 Months
B1 100% 100% 93%
B2 100% 93% 80%
B3 100% 100% 98%
B6 100% 100% 97%
B12 100% 100% 100%
C 100% 100% 97%
6. Remark
Due to the high loss of riboflavin phosphate sodium it should be substituted
by riboflavin.
关键字：vitamin complex
