VitaminBComplex VitaminC
CalciumEffervescentTablets
1.Formulation
I.Thiaminemononitrate（BASF）.......................7g Riboflavin（BASF）.........................................5g Nicotinamide.............................................25g Pyridoxinehydrochloride（BASF）.................20g CalciumD-panto thenate（BASF）.................12g Calciumcarbonate....................................75g Calciumglycerophosphate.......................164g Sodiumbicarbonate................................400g Tartaricacid,powder...............................300g Sucrose,crystalline.................................400g Sucrose,powder.....................................350g Kollidon30[1]...........................................50g
II.Kollidon30[1]...........................................10g Isopropanol................................................q.s.
III.Ascorbicacid,powder（BASF）..................550g Riboflavin（BASF）.........................................2g Cyanocobalamingelatincoated0.1%...........5g （BASF）.............................................................
Polyethyleneglycol6000,powder[6]..........40g KollidonCL[1]..........................................50g 2.Manufacturing（Wetgranulation）
GranulatemixtureIwithsolutionII,dryat60Cwithvacuum,mixwithIII
andpresswithmediumto highcompressionforce.
3.Tabletproperties
Weight..............................................2,500mg Diameter...............................................20mm
Form...................................................biplanar
Hardness................................................150N
Disintegration..........................................2min
Friability...................................................0.9%
关键字：vitamin complex
