Multivitamin Effervescent Granules

MultivitaminEffervescentGranules （1RDAofVitamins） 1.Formulation I.Thiaminhydrochloride（BASF）..................0.26g Riboflavin（BASF）....................................0.30g Nicotinamide..........................................1.10g Pyridoxinehydrochloride（BASF）..............0.25g CalciumD-panto thenate（BASF）..............1.50g Ascorbicacid,powder（BASF）...............20.00g Citricacid............................................50.00g Sucrose.............................................130.00g Fructo se..............................................80.00g KollidonCL-M[1]..................................20.00g Flavours...............................................25.00g Cyclamatesodium..................................2.00g Saccharinesodium.................................0.10g II.KollidonVA64[1].................................15.00g Isopropanol..........................................35.00g III.VitaminAacetate drypowder325000I.U./gCWD（BASF）..1.50g VitaminD3drypowder 100000I.U./gCWD（BASF）....................0.80g VitaminEacetate drypowder50%.....................................2.10g Cyanocobalamingelatin..........................0.66g coated0.1%（BASF） Sodiumbicarbonate.............................40.00g 2.Manufacturing GranulatemixtureIwithsolutionII,pass througha0.8mmsieve,dry wellandmixwithIII. Fill3–4ginsachets.3. Properties of the granulesColour: Yellow granulesFlowability: Very goodDispersibility: 4 g disperse homogeneously in waterafter about 40 seconds.4. Administration3 – 4 g of the granules （= 1 sachet） correspond to about 1 RDA of thevitamins