VitaminB1 CaffeineTablets
（500mg 100mg）
1.Formulation
I.Thiaminehydrochloride（BASF）......................500g Caffeine（BASF）............................................100g Cornstarch[3]...............................................30g KollidonVA64[1]...........................................20g
II.KollidonVA64[1]...........................................15g Ethanol96%...................................................q.s.
III.Polyethyleneglycol6000,powder[6]..............35g 2.Manufacturing（Wetgranulation）
GranulatemixtureIwithsolutionII,dry,sieve,mixwithIIIandpresswith
lowcompressionforce.
3.Tabletproperties
Weight......................................................698mg Diameter....................................................16mm
Form........................................................biplanar
Hardness.....................................................101N
Disintegration...............................................2min
Friability.......................................................0.5%
关键字：vitamin caffeine tablets
