MetamizolTablets
（500mg）
1.Formulations
No.1No.2
Metamizolsodium........................................500g500g （=Dipyrone）
Ludipress[1]................................................100g–
AvicelpH101[5].................................................–100g Kollidon30[1].....................................................–15g KollidonCL[1]...............................................10g25g Magnesiumstearate[2]...................................10g–
Aerosil200[4]..................................................5g1g Talc[10]..............................................................–8g Calciumarachinate[2].........................................–1g 2.Manufacturing（Directcompression）
Mixallcomponents,pass througha0.5mmsieveandpresswithlow
compressionforce.
3.Tabletproperties
No.1No.2
Weight......................................................625mg654mg Diameter....................................................12mml2mm
Form........................................................biplanarbiplanar
Hardness.....................................................120N62N
Disintegration...............................................5min2min
Friability.......................................................0.3%1%
关键字：metamizol tablets
