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SulfadimethoxineVeterinary Injectable Solution (2.5%=250mg/10ml) 1.Formulation I.Sulfadimethoxine.........................................5g Ethanol96%...........................................40ml Propyleneglycol[1]..................................40ml II.Kollidon12PF[1]......................................70g Antioxidant................................................q.s. WaterforInjectable s..................q.s.ad200ml 2.Manufacturing MixSolution IslowlywithSolution IIat60Candcool. 3.PropertiesoftheSolution Appearance..............................................clear pH.................................................................7 Viscosity..............................................verylow 4.Physicalstability(20–25C) Norecrystallisationaftersomeweeks. 5.Remark to prevento fdiscolourationofKollidonintheSolution duringsto rage0.2 to 0.5%ofcysteinecouldbeaddedasantioxidant.
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