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MiconazoleInjectable Solution (1%) 1.Formulation I.Miconazole..............................................1.0g CremophorEL[1]...................................12.0g II.Parabenes.................................................q.s. WaterforInjectable s..........................ad100ml 2.Manufacturing HeatmixtureIto about65C,stirwellandaddslowlythehotSolution II. Aftertheampouleshavebeenheat-sterilized,theyshouldbeshakenfor ashorttime,whiletheyarestillhot,to eliminateanyseparationofthe phasesthatmayhaveoccurred.Sterilizationcanalsobeperformedby membranefiltrationunderpressure. 3.PropertiesoftheSolution Clearcolourlessliquidhavingalowviscosity.
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