Betamethasone NeomycinGel-Cream
(0.1% 0.6%)
1.Formulation
Betamethasonevalerate..........................0.13g Neomycinsulfate....................................0.65g LutrolE400[1].....................................15.00g Miglyol812(Dynamit-Nobel)...............10.00g LutrolF127[1].....................................20.00g Water............................................ad100.00g 2.Manufacturing DissolvebetamethasonevalerateinthemixtureofLutrolE400and
Miglyol812.
DissolveLutrolF127andneomycinsulfateinwaterat5–10C.Mixboth
solutions.Maintaincooluntiltheairbubblesdisappeared.
3.Propertiesofthegel-cream
Amilkywhitesoftgel-creamisobtained.
关键字:betamethasone neomycin gel