Povidone-IodineSeamlessSolution s
(10%)
1.Formulations
No.1No.2
PVP-Iodine30/06(BASF).............................10.0g10.0g NatrosolHR250(Hercules).........................1.0g–
LutrolF127[1]..............................................0.2g–
Sodiumhydroxide,1molarSolution ................3.2g–
TyloseM300(Hoechst).....................................–2.0g TexaponK12(Henkel).........................................–0.2g CitricacidSolution 0.1molar................................–59.5g SodiumbiphosphateSolution 0.2molar................–28.3g Water.........................................................85.6g–
2.Manufacturing FormulationNo.1:
DissolveLutrolF127andthanNatrosolinthewater.Assoonasboth
aredissolvedaddslowlythePVP-Iodineto thewellstirredSolution .
AdjustthepHwiththesodiumhydroxideSolution to about3.5.
FormulationNo.2:
DissolveTyloseM300inthemixtureofthecitricacidandsodium
biphosphateSolution s,addTexaponandslowlydissolvethePVP-Iodine.
3.PropertiesoftheSolution s
Brown,clearSolution shavingacertainviscosityandapHof3–4.
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