Povidone-IodineLozenges
（5mg）
1.Formulations
PVP-Iodine30/06M10（BASF）.................5.0g Sorbito l,cryst.[10]...............................150.0g Menthol,crystalline...........................4.0–5.0g Eucalypto l,crystalline.......................4.0–5.0g Aspartame,potassium（Searle）..................1.0g Saccharin,sodium....................................0.1g Aerosil200[4]..................................2.0–3.0g Magnesiumstearate[2].............................1.0g 2.Manufacturing（Directcompression）
Mixallcomponents,pass througha0.8mmsieveandpresswith
mediumcompressionforce.
3.Tabletproperties
Weight.................................................176mg Diameter.................................................8mm
Form...................................................biplanar
Hardness................................................100N
Disintegrationinwater..........................>10min
Friability...................................................0.2%
4.Chemicalstability（14daysat52C）
Thelossofavailableiodinewas16%.
关键字：povidone iodine lozenges
