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AluminiumHydroxide MagnesiumHydroxideChewableTablets (200mg 200mg) 1.Formulation I.Aluminiumhydroxide(Rorer).....................200g Magnesiumhydroxide(Rorer)...................200g Lacto semonohydrate[8]..........................100g II.KollidonVA64[1]......................................30g Water......................................................260g III.Sucrose,crystalline..................................315g Sorbito l,crystalline(Merck)......................100g Polyethyleneglycol6000,powder[6]..........60g Aerosil200[4]...........................................12g Talc[10]......................................................6g Magnesiumstearate[2]...............................6g 2.Manufacturing(Wetgranulation) GranulatemixtureIwithsolutionII,dry,pass througha0.8mmsieve, addIIIandpresswithhighcompressionforce(20kN). 3.Tabletproperties Weight................................................1013mg Diameter...............................................16mm Form...................................................biplanar Hardness................................................131N Disintegration........................................27min Friability...................................................0.2%

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