AminophyllineTablets （90mg） 1.Formulations No.1No.2 I.Aminophylline,hydrouspowder（BASF）...........90g90g Potato starch[3]............................................80g– Cornstarch[3]....................................................–74g KollidonVA64[1].............................................3g3g
II.KollidonVA64[1].............................................3g3g Water............................................................30g27g III.Magnesiumstearate[2]....................................1g– Talc[10]...........................................................4g– Polyethyleneglycol6000,powder[6]...................–10g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,pass througha0.8mmsieve,dry, mixwithIII,pass througha0.5mmsieveandpressto tabletswith mediumcompressionforce. 3.Tabletproperties No.1No.2 Weight......................................................179mg180mg Diameter......................................................8mm8mm Form........................................................biplanarbiplanar Hardness......................................................80N72N Disintegration..........................................3–4min6–7min Friability.......................................................0.4%0.4%
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