Aluminium Acetylsalicylate Tablets

AluminiumAcetylsalicylateTablets （250mg） 1.Formulation I.Aluminiumacetylsalicylate........................255g Mannito l..................................................213g Cornstarch[3]..........................................28g II.Kollidon90F[1]........................................10g LutrolE6000[1]..........................................5g Isopropanol.....................................about50g III.KollidonCL[1]..........................................23g Magnesiumstearate[2]...............................5g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,dry,pass througha0.8mmsieve, mixwithIIIandpresswithmediumcompressionforce. 3.Tabletproperties Weight.................................................540mg Diameter...............................................12mm Form...................................................biplanar Hardness................................................110N Disintegration......................................1–2min Friability...................................................0.4%