VerapamilSustainedReleaseTablets
（220mg）
1.Formulation
Verapamilhydrochloride........................240.0g LudipressLCE[1].................................230.0g MethocelK15M（Dow）.............................75.0g Talc.......................................................75.0g Magnesiumstearate[2].............................5.0g Aerosil200[4]..........................................2.5g 2.Manufacturing（Directcompression）
Mixallcomponents,pass througha0.8mmsieveandpresswithlow
compressionforceusingavibratinghopper.
3.Tabletproperties
Weight.................................................628mg Diameter...............................................12mm
Form...................................................biplanar
Hardness................................................100N
Friability...................................................0.1%
Massuniformity（srel.）............................1.75%
关键字：verapamil sustained release
