Mefenamic Acid Tablets

MefenamicAcidTablets （250mg） 1.Formulation I.Mefenamicacid.......................................250g Cornstarch[3]..........................................40g II.Kollidon90F[1]..........................................5g Isopropanol................................................q.s. III.KollidonCL[1]...........................................12g AvicelpH101[5].......................................85g Magnesiumstearate[2]...............................5g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,sieve,dry,addmixtureIIIandpress withmediumcompressionforce. 3.Tabletproperties Weight.................................................404mg Diameter...............................................12mm Form...................................................biplanar Hardness..................................................70N Disintegration..........................................2min Friability...................................................0.8%