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CarbamazepineSustainedReleaseTablets
(200mg)DC
1.Formulations
AB
Carbamazepine(Fabricaital.Sintetica).......200.0g200.0g KollidonSR[1]...........................................100.0g100.0g LudipressLCE[1]......................................200.0g150.0g KollidonCL-M[1]................................................–20.0g Magnesiumstearate[2].................................2.5g2.5g 2.Manufacturing(Directcompression)
Allingredientswerepass edthrougha0.8mmsieve,blendedfor10min
inaTurbulamixerandthecompressedwithhighcompressionforce.
3.Tabletproperties
AB
Weight...................................................502.5mg472.5mg Diameter....................................................12mml2mm
Hardness.....................................................140N164N
Friability......................................................0.14%0.06%
关键字:carbamazepine sustained release
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