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DiclofenacSustainedRelease
Tablets
(100mg)
1.Formulation
Diclofenacsodium(Ivotec).....................100.0g KollidonSR[1]......................................100.0g Silicondioxide,colloidal[4].......................3.4g Magnesiumstearate[2].............................3.4g 2.Manufacturing(Directcompression)
Allingredientswerepass edthrougha0.8mmsieve,blendedfor10min
inaTurbulamixerandthencompressedwithmediumcompressionforce.
3.Tabletproperties
Weight..............................................206.4mg Diameter.................................................8mm
Hardness................................................195N
Friability.................................................0.09%
关键字:diclofenac sustained release
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