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SugarFilmCoating 1.Formulationofthecoatingsuspension
Sucrose..................................................200g KollidonVA64[1].......................................50g SicovitTitaniumdioxide[1]........................30g SicovitIronoxide[1]..................................15g Macrogol4000..........................................40g Talc..........................................................50g Water...............................................ad1200g 2.Manufacturingofthecoatingsuspension
Dissolvethesucrose,KollidonVA64andMacrogol4000inthewaterand
suspendtheothercomponents.Passthroughacolloidmill.
3.Coatingprocedure(AccelaCota24’’)
Tabletcoreloading.................................5.0kg Amounto fcoatingsuspension................1.2kg Inletairtemperature................................45C
Outletairtemperature..............................36C
Nozzle..................................................0.8mm
Rotationspeedofthepan......................15rpm
Sprayingpressure.................................2.0bar
Sprayingtime(continuously)...................50min
Quantityoffilmformerapplied...........4mg/cm2
关键字:sugar film coating
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