ProtectiveFilmCoatingwithKollidonVA64 PolyvinylAlcohol 1.Formulation I.KollidonVA64[1]......................................50g LutrolE6000[1].........................................12g Polyvinylalcohol（Mowiol8-88,Hoechst）..76g Water......................................................840g
II.SicovitTitaniumdioxide[1]........................37g SicovitIronoxideRed[1]...........................18g Talc..........................................................56g Water......................................................168g .............................................................1257g 2.Manufacturingofthesuspension DissolveLutrolE6000andKollidonVA64in840mlofwater,addthe polyvinylalcoholandstirr45minavoidingtheformationofto omuchof airbubbles. Suspend thepigmentsandtalcin168mlofwaterandpass thismixture throughacolloidmill. to obtainthefinalcoatingsuspensionmixsolutionIwithsuspension
II. 3.Coatingprocedure（AccelaCota24’’） Loadingoftabletcores..........................5.0kg （9mm,biconvex,about3cm2） Amounto fcoatingsuspension...............1.26kg Inletairtemperature................................59C Outletairtemperature..............................46C Nozzle..................................................1.0mm Rotationspeedofthepan......................15rpm Sprayingpressure.................................2.0bar Sprayingrate......................................15g/min Sprayingtime（continuously）...................83min Finaldrying..............................................5min Quantityoffilmformer............about3mg/cm2 applied
关键字：protective film coating
