Protective Film Coating with Kollidon VA 64 Ethyl Cellulose

ProtectiveFilmCoatingwithKollidonVA64 EthylCellulose 1.Formulation I.KollidonVA64[1]........................................5g Ethocel20（Dow）......................................5g SicovitTitaniumdioxide[1]........................20g Talc...........................................................13g SicovitIronoxide[1]..................................q.s. Isopropanol...............................................98g Water........................................................59g II.Isopropanol.............................................140g Water........................................................60g 2.Manufacturingofthesuspension DissolveEthocelandKollidonVA64inisopropanol,addthewaterand suspendthecolorantsandthetalc.Passthismixturethroughacolloid millandaddsolution II. 3.Coatingprocedure（Fludizedbed） Tabletcoreloading....................................5kg Inletairtemperature................................40C Outletairtemperature..............................38C Inletflap..........................................Position10 Outletflap..........................................Posito n4 Sprayingpressure....................................3bar Sprayingtime.........................................15min Finaldrying..............................................2min Quantityoffilmformingagent/cm2............1mg