Paracetamol（=Acetaminophen） Supposito ries（150mgand500mg） 1.Formulations No.1No.2 150mg500mg I.Paracetamol,finepowder............................15.4g50.0g Aerosil200[4]...............................................0.2g–
II.LutrolE400[1]...................................................–10.0g Macrogol1500..........................................129.0g60.0g Macrogol4000............................................55.4g80.0g 2.Manufacturing MeltthemixtureIIandsuspendthemixtureI.Fillthemoltenmassinthe mouldsofsupposito ries. 3.Propertiesofthesupposito ries Weight.....................................................2.0g Solubilityinwater......................................easy Colour..............................................colourless 4.Physicalstability（FormulationNo.1） Nocrystallisationafterthesto rageof6weeksat6C,20Cor40C.
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