Paracetamol(=Acetaminophen) Ibuprofen OrphenadrinTablets
(250mg 200mg 100mg)
1.Formulation
Paracetamol,powder<300μm...............250g Ibuprofen................................................200g Orphenadinehydrochloride......................100g Ludipress[1]...........................................200g Magnesiumstearate[2]...............................5g Aerosil200[4].............................................5g 2.Manufacturing(Directcompression)
Passallcomponentsthrougha0.5mmsieve,mixandpresswithhigh
compressionforce.
3.Tabletproperties
Weight.................................................761mg Diameter...............................................12mm
Form...................................................biplanar
Hardness..................................................74N
Disintegration..........................................6min
Friability...................................................0.7%
关键字:paracetamol acetaminophen ibuprofen